3-氨基-1-甲基-5H-吡啶[4,3-B]吲哚合成路线 （共 20 条）
反应条件
aluminium trichloride T=90°C; 18 h;
参考文献
Tetrahedron, , vol. 59, # 40 p. 8003 - 8010
反应条件
1: 87 percent / thionyl chloride / Heating 2: 98 percent / sulfur / xylene / Heating; lead tetraacetate as reagent in pyridine; 3: 96 percent / aq.NaOH / ethanol / Heating 4: diphenylphosphoryl azide; triethylamine; acetic acid; NaOH; View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, p. 123 - 130
反应条件
1: 95 percent / Na2CO3 / H2O / Heating 2: 87 percent / thionyl chloride / Heating 3: 98 percent / sulfur / xylene / Heating; lead tetraacetate as reagent in pyridine; 4: 96 percent / aq.NaOH / ethanol / Heating 5: diphenylphosphoryl azide; triethylamine; acetic acid; NaOH; View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, p. 123 - 130
反应条件
1: 98 percent / Na2CO3 / H2O / 15 h / Heating 2: 87 percent / thionyl chloride / Heating 3: 98 percent / sulfur / xylene / Heating; lead tetraacetate as reagent in pyridine; 4: 96 percent / aq.NaOH / ethanol / Heating 5: diphenylphosphoryl azide; triethylamine; acetic acid; NaOH; View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, p. 123 - 130
反应条件
1: 98 percent / sulfur / xylene / Heating; lead tetraacetate as reagent in pyridine; 2: 96 percent / aq.NaOH / ethanol / Heating 3: diphenylphosphoryl azide; triethylamine; acetic acid; NaOH; View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, p. 123 - 130
反应条件
1: 24 percent / phosphoryl chloride / 2 h / 85 °C 2: 58 percent / 20percent methanolic ammonia / 5 h / 100 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, p. 123 - 130
反应条件
T=400 - 500°C; 1 h; Further byproducts given;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 56, # 5 p. 1450 - 1454
反应条件
copper; NOBF4
0.5 h; Ambient temperature;
参考文献
Hashimoto; Shudo; Okamoto
Chemical and pharmaceutical bulletin, 1984 , vol. 32, # 11 p. 4300 - 4308
反应条件
rat S9 mix; NADPH in phosphate buffer
Oxidation; hydroxylation; pH=7.4;
参考文献
Hashimoto; Shudo; Okamoto
Chemical and pharmaceutical bulletin, 1984 , vol. 32, # 11 p. 4300 - 4308
反应条件
sodium tungstate; dihydrogen peroxide in acetonitrile
12 h;
参考文献
Hashimoto; Shudo; Okamoto
Chemical and pharmaceutical bulletin, 1984 , vol. 32, # 11 p. 4300 - 4308
