反式-4-氨基环己烷羧酸甲酯合成路线 （共 11 条）
反应条件
1: 531 g / triethylamine / CHCl3 / 5 h / 20 °C
2: 301 g / lithium aluminum hydride / diethyl ether / 2 h / 20 °C
3: 27.5 g / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran; toluene / 60 h / 20 °C
4: hydrazine hydrate / ethanol / 2.25 h / Heating
View Scheme
参考文献
Kanuma, Kosuke; Omodera, Katsunori; Nishiguchi, Mariko; Funakoshi, Takeo; Chaki, Shigeyuki; Nagase, Yasuko; Iida, Izumi; Yamaguchi, Jun-ichi; Semple, Graeme; Tran, Thuy-Anh; Sekiguchi, Yoshinori
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 10 p. 3307 - 3319
