7-苄基-5,6,7,8-四氢吡啶并[3,4-d]嘧啶-4(3H)-酮合成路线 （共 5 条）
反应条件
1: With sodium methylate in methanol T=25°C; 20 h; 2: With acetic acid in methanol; water T=0 - 25°C;
参考文献
WO2009/158396 A1, ;
Page/Page column 67 ;
反应条件
1: With sodium methylate in methanol T=20°C; 20 h; 2: With acetic acid in methanol T=10°C; 1 h;
参考文献
WO2005/42537 A1, ;
Page/Page column 85 ;
WO 2005/042537 A1
反应条件
sodium methylate in methanol 2 h; Heating / reflux;
参考文献
WO2005/66171 A1, ;
Page/Page column 58-59 ;
WO 2005/066171 A1
反应条件
1: With N-ethyl-N,N-diisopropylamine; trichlorophosphate in toluene T=100°C; 0.5 h; 2: With sodium hydrogencarbonate in water; toluene T=20°C; 1 h;
参考文献
WO2005/42537 A1, ;
Page/Page column 86 ;
WO 2005/042537 A1
反应条件
hydrogenchloride in water
T=20°C;
参考文献
RENOVIS, INC.
Patent: WO2007/28022 A2, 2007 ;
Location in patent: Page/Page column 41-42 ;
