反应条件
1: 3-(trifluoromethyl)-5,8-dihydro-1,6-naphthyridin-7(6H)-one With borane-THF in tetrahydrofuran
T=20°C;
2: di-tert-butyl dicarbonate With N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C;
参考文献
Goble, Stephen D.; Yang, Lihu; Zhou, Changyou; Kothandaraman, Shankaran; Guiadeen, Deodialsingh; Butora, Gabor; Pastemak, Alexander; Mills, Sander G.
Patent: US2007/117797 A1, 2007 ;
Location in patent: Page/Page column 24 ;
US 20070117797 A1