pyridine; 4-(N,N-dimethlyamino)pyridine in dichloromethane
T=25°C; 16 h;
参考文献
Patterson, Stephen; Alphey, Magnus S.; Jones, Deuan C.; Shanks, Emma J.; Street, Ian P.; Frearson, Julie A.; Wyatt, Paul G.; Gilbert, Ian H.; Fairlamb, Alan H.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6514 - 6530
1.1: n-butyllithium / diethyl ether; hexane / 2 h / -78 - 0 °C
1.2: 2 h / 0 °C
2.1: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 16 h / 25 °C
View Scheme
参考文献
Patterson, Stephen; Alphey, Magnus S.; Jones, Deuan C.; Shanks, Emma J.; Street, Ian P.; Frearson, Julie A.; Wyatt, Paul G.; Gilbert, Ian H.; Fairlamb, Alan H.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6514 - 6530
