N-亚苄基-N-(二苯甲基)胺合成路线 （共 17 条）
反应条件
1: 58 percent / (S)-BLA / CH2Cl2; toluene / 20 h / -78 °C 2: 99.5 percent / conc. H2SO4 / 2 h / Heating 3: 95 percent / H2 / Pd/C / methanol / 2.5 h / 25 °C / 760 Torr View Scheme
参考文献
Kuroki, Yoshichika; Ishihara, Kazuaki; Hanaki, Naoyuki; Ohara, Suguru; Yamamoto, Hisashi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 5 p. 1221 - 1230
反应条件
1: sodium hydride / hexamethylphosphoric acid triamide; tetrahydrofuran 2: sodium hydride / tetrahydrofuran; hexamethylphosphoric acid triamide 3: aq. H2SO4 / Ambient temperature 4: aq. H2SO4 / Ambient temperature View Scheme
参考文献
Armesto, Diego; Ortiz, Maria J.; Perez-Ossorio, Rafael
Tetrahedron Letters, 1981 , vol. 22, # 23 p. 2203 - 2206
反应条件
1: 0.5 h / 130 - 140 °C / Heating 2: conc. hydrochloric acid / 3 h / Heating View Scheme
参考文献
Green, Donovan; Patel, Geeta; Elgendy, Said; Baban, Jehan A.; Claeson, Goran; Kakkar, Vijay V.; Deadman, John
Tetrahedron, 1994 , vol. 50, # 17 p. 5099 - 5108
反应条件
hydrogenchloride multistep reaction: 1.) 130-140 deg C, 30 min, 2.) 3 h, reflux; reactions of derivatives; Product distribution;
参考文献
Green, Donovan; Patel, Geeta; Elgendy, Said; Baban, Jehan A.; Claeson, Goran; Kakkar, Vijay V.; Deadman, John
Tetrahedron, 1994 , vol. 50, # 17 p. 5099 - 5108
反应条件
1: 0.5 h / 130 - 140 °C / Heating 2: conc. hydrochloric acid / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 50, # 17 p. 5099 - 5108
反应条件
hydrogenchloride multistep reaction: 1.) 130-140 deg C, 30 min, 2.) 3 h, reflux; reactions of derivatives; Product distribution;
参考文献
Tetrahedron, , vol. 50, # 17 p. 5099 - 5108
反应条件
1: 95 percent Spectr. / cyclo<(S)-Phe-(S)-α-amino-γ-guanidinobutyric acid> / methanol / -25 °C 2: aq. HCl / 6 h / 60 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 20 p. 4910 - 4911
反应条件
1: 90 °C 2: 60percent HBr / 6 h / 100 °C View Scheme
参考文献
Issleib, Kurt; Doepfer, Klaus-Peter; Balszuweit, Arno
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1981 , vol. 36, # 11 p. 1392 - 1394
反应条件
1: H3PO2 2: aq. HBr View Scheme
参考文献
CIBA-GEIGY
Patent: DE2722162 , 1977 ;
Chem.Abstr., 1978 , vol. 88, # 105559
反应条件
sodium in 1,4-dioxane 15 h; Heating; Mechanism;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 19, # 1 p. 72 - 73
