potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); tri-cyclo-hexyl-phosphine in 1,4-dioxane; water T=80 - 100°C; Suzuki Coupling; Inert atmosphere;

1.1: oxygen / 0.5 h / Reflux 2.1: potassium hexacyanoferrate(III); sodium hydroxide; water / 2 h / Cooling with ice 2.2: pH ~ 8 3.1: phosphorus pentachloride; trichlorophosphate / 8 h / Inert atmosphere; Reflux 4.1: potassium phosphate / tri-cyclo-hexyl-phosphine; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane; water / 80 - 100 °C / Inert atmosphere View Scheme

1: phosphorus pentachloride; trichlorophosphate / 8 h / Inert atmosphere; Reflux 2: potassium phosphate / tri-cyclo-hexyl-phosphine; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane; water / 80 - 100 °C / Inert atmosphere View Scheme