2'',3''-二氢-2H,5H-螺[咪唑烷-4,1''-茚]-2,5-二酮合成路线 (共 6 条)
反应条件
barium dihydroxide in water T=150°C;
参考文献
Chruma, Jason J.; Liu, Lei; Zhou, Wenjun; Breslow, Ronald
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 20 p. 5873 - 5883
反应条件
(NH4)2CO3 in ethanol
T=55 - 75°C; 24 h;
参考文献
Sarges; Schnur; Belletire; Peterson
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 230 - 243
反应条件
in ethanol; water
T=55 - 60°C; Bucherer-Bergs reaction;
参考文献
Pesquet, Anthony; Daich, Adam; Van Hijfte, Luc
Journal of Organic Chemistry, 2006 , vol. 71, # 14 p. 5303 - 5311
反应条件
in ethanol; water
T=50°C; 144 h;
参考文献
Li, Xiang-Guo; Rantapaju, Maria; Kanerva, Liisa T.
European Journal of Organic Chemistry, 2011 , # 9 p. 1755 - 1762
反应条件
in ethanol; water
T=45°C; Bucherer Bergs reaction; 5 h; sonication;
参考文献
Chruma, Jason J.; Liu, Lei; Zhou, Wenjun; Breslow, Ronald
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 20 p. 5873 - 5883
参考文献
Henze; Speer
Journal of the American Chemical Society, 1942 , vol. 64, p. 522
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Tiffeneau; Tchoubar; Saiaslambert
Bulletin de la Societe Chimique de France, 1947 , p. 445,448
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Faust et al.
Journal of the American Pharmaceutical Association (1912-1977), 1957 , vol. 46, p. 118,122