hydrogenchloride in diethyl ether; tert-butyl methyl ether T=5°C; Product distribution / selectivity;

1: With sodium hydrogencarbonate in methanol T=67°C; 0.5 - 4 h; Heating / reflux; 2: With sodium tetrahydroborate in methanol T=0 - 20°C; 18 h; 3: With water in dichloromethane Product distribution / selectivity;

dimethylsulfide borane complex in tetrahydrofuran T=60°C;

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 0 - 20 °C / |Inert atmosphere 2: dimethylsulfide borane complex / tetrahydrofuran / 60 °C View Scheme