N-叔丁氧羰基-L-色氨酰胺合成路线 (共 6 条)
反应条件
pyridine; di-tert-butyl dicarbonate; NH4HCO3 in acetonitrile 4-16 h;
参考文献
Pozdnev, Vladimir F.
Tetrahedron Letters, 1995 , vol. 36, # 39 p. 7115 - 7118
反应条件
4-methyl-morpholine; ammonia in methanol; dichloromethane
参考文献
US5223516 A1, ;
US 5223516 A
反应条件
triethylamine in dichloromethane
反应条件
ammonium hydroxide; HATU in N,N-dimethyl-formamide T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 18 p. 5392 - 5396
反应条件
triethylamine in tetrahydrofuran; benzene
参考文献
E. R. Squibb and Sons, Inc.
Patent: US5223516 A1, 1993 ;
US 5223516 A
反应条件
triethylamine; trifluoroacetic anhydride in tetrahydrofuran T=0°C;
参考文献
Guay, Daniel; Beaulieu, Christian; Jagadeeswar Reddy; Zamboni, Robert; Methot, Nathalie; Rubin, Joel; Ethier, Diane; David Percival
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 18 p. 5392 - 5396