1: With sodium hydride in tetrahydrofuran Reflux; 2: With acetic acid in tetrahydrofuran

1: (S)-1,2,3,4-tetrahydro-2-naphthoic acid With 1,1'-carbonyldiimidazole in tetrahydrofuran T=20°C; 2: malonic acid ethyl ester monopotassium salt With triethylamine; magnesium chloride in tetrahydrofuran; acetonitrile T=20°C; Cooling with ice; 3: With hydrogenchloride; water in toluene T=20°C; Cooling with ice;

1: propanedioic acid monoethyl ester With [2,2']bipyridinyl; n-butyllithium in tetrahydrofuran; hexane T=-78 - -5°C; 0.25 h; y; 2: 1,2,3,4-tetrahydro-2-naphthoyl chloride in tetrahydrofuran; hexane T=-70°C; 1 h; Further stages.;

niobium pentachloride in dichloromethane T=27°C; 5 h;

1: ethyl naphthalen-2-carboxylate With sodium hydride in anhydrous butyl ether T=100°C; 2: ethyl acetate in anhydrous butyl ether T=100°C; 6.5 h; Reflux; 3: With hydrogenchloride; water in diethyl ether pH=2; Cooling with ice;

in diethyl ether; n-heptane; water; ethyl acetate; toluene; mineral oil; carbonic acid diethyl ester

sodium methylate