(2,6-二氧代-4-哌啶)-乙酸合成路线 （共 8 条）
反应条件
hydrogenchloride 1) H2O, reflux, 15 h, 2) at 235 deg C, 5 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, p. 341 - 343
反应条件
1: 96 percent / hydrogen / 10percent Pd/C / ethanol / 5 h 2: 60 percent / hydrochloric acid / 1) H2O, reflux, 15 h, 2) at 235 deg C, 5 h View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, p. 341 - 343
反应条件
1: 90 percent / ammonium acetate, acetic acid / benzene / 24 h / Heating 2: 96 percent / hydrogen / 10percent Pd/C / ethanol / 5 h 3: 60 percent / hydrochloric acid / 1) H2O, reflux, 15 h, 2) at 235 deg C, 5 h View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, p. 341 - 343
反应条件
ammonium hydroxide T=200°C;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 24, p. 1297,1301
反应条件
sulfuric acid; acetic acid
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 6 p. 1726 - 1728
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 58, # 11 p. 1436 - 1441
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 24, p. 1297,1301
反应条件
1.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere 1.2: 1.5 h / 20 °C / |Inert atmosphere 2.1: triethylsilane; 5 palladium on charcoal / tetrahydrofuran / 7 h / |Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 23 p. 7370 - 7383
