1: nitroacetic acid ethyl ester With titanium tetrachloride in tetrahydrofuran
T=0°C; 0.0833333 h;
2: tetrahydro-pyran-4-one With 4-methyl-morpholine in tetrahydrofuran
T=20°C; 18 h; Title compound not separated from byproducts;
参考文献
Strachan, Jon-Paul; Whitaker, Regina C.; Miller, Craig H.; Bhatti, Balwinder S.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9909 - 9911