甲基4-吗啉二硫代甲酸酯合成路线 （共 11 条）
反应条件
1: morpholine; carbon disulfide With sodium hydroxide in water T=20°C; 1 h; Inert atmosphere; 2: dimethyl sulfate in water T=5 - 20°C; 1 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BARLAAM, Bernard, Christophe; DEGORCE, Sebastien Louis; LAMBERT-VAN DER BREMPT, Christine Marie Paul; LOHMANN, Jean-Jacques Marcel; PLE, Patrick
Patent: WO2012/140419 A1, 2012 ;
Location in patent: Page/Page column 85 ;
反应条件
in ethanol dithiocarboxylation; 3 h; Heating;
参考文献
Mohanta, Pramod K.; Dhar, Sanchita; Samal; Ila; Junjappa
Tetrahedron, 2000 , vol. 56, # 4 p. 629 - 637
反应条件
in ethanol dithiocarboxylation; 2.5 h; Heating;
参考文献
Mohanta, Pramod K.; Dhar, Sanchita; Samal; Ila; Junjappa
Tetrahedron, 2000 , vol. 56, # 4 p. 629 - 637
参考文献
Journal of the American Chemical Society, , vol. 70, p. 4143,4149
反应条件
in acetonitrile T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 22 p. 7310 - 7314
反应条件
sodium hydroxide 1 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 28, # 4 p. 347 - 352
反应条件
1.) THF, 30 deg C, 3 h, 2.) THF, 30 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Synthetic Communications, , vol. 22, # 9 p. 1231 - 1238
反应条件
1.) THF, 30 deg C, 3 h, 2.) THF, 30 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Synthetic Communications, , vol. 22, # 9 p. 1231 - 1238
参考文献
Stansfield,F.; Coomassie,M.D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 2708 - 2710
反应条件
in benzene
1) 0 deg C, 10 min, 2) r.t., 3 to 5h;
参考文献
Tominaga, Yoshinori; Matsuoka, Yoshiki; Kohra, Shinya; Hosomi, Akira
Heterocycles, 1987 , vol. 26, # 3 p. 613 - 616
