sulfuric acid in benzene

1: para-iodoanisole With palladium diacetate; caesium carbonate; di-(1-adamantyl)-n-butylphosphine in toluene T=20 - 100°C; Inert atmosphere; 2: 2,6-dimethylphenyl isocyanide in toluene T=100°C; 4 h; Inert atmosphere;

N,N-dimethyl-aniline in xylene T=150°C; 15 h;

1.1: triethylamine; trichlorophosphate / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere 2.1: palladium diacetate; caesium carbonate; di-(1-adamantyl)-n-butylphosphine / toluene / 20 - 100 °C / Inert atmosphere 2.2: 4 h / 100 °C / Inert atmosphere View Scheme

1.1: acetic anhydride / dichloromethane / 2 h / 20 °C / Inert atmosphere 2.1: triethylamine; trichlorophosphate / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere 3.1: palladium diacetate; caesium carbonate; di-(1-adamantyl)-n-butylphosphine / toluene / 20 - 100 °C / Inert atmosphere 3.2: 4 h / 100 °C / Inert atmosphere View Scheme