5-甲基硫代-1,3,4-噻二唑-2-硫醇合成路线 （共 5 条）
反应条件
potassium hydroxide in water 1 h;
参考文献
Organic Magnetic Resonance, , vol. 16, # 1 p. 1 - 6
反应条件
in argon matrix T=-263.16°C; 2.75 h; UV-irradiation;
参考文献
Journal of Physical Organic Chemistry, , vol. 23, # 1 p. 56 - 66
反应条件
potassium hydroxide in ethanol
参考文献
Mistry, Jigar K.; Dawes, Richard; Choudhury, Amitava; Van De Mark, Michael R.
Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 3 p. 747 - 754
反应条件
1: 2-methylmercapto-5-mercapto-1,3,4-thiadiazole With sodium hydride in N,N-dimethyl-formamide; benzene
T=0°C; 0.25 h;
2: 3-chloro-2-pyrazinecarbonitrile in N,N-dimethyl-formamide; benzene
T=80°C; 4 h;
参考文献
Amgen Inc.
Patent: US2008/96900 A1, 2008 ;
Location in patent: Page/Page column 22-23 ;
反应条件
in ethanol; water
0.5 h; Heating;
参考文献
Pappalardo, Sebastiano; Bottino, Francesco; Tringali, Corrado
Journal of Organic Chemistry, 1987 , vol. 52, # 3 p. 405 - 412
