N-(4-苯并噻唑-2-基-苯基)-乙酰胺合成路线 （共 8 条）
反应条件
acetic anhydride in benzene
参考文献
Cancer Research Campaign Technology Limited
Patent: US6034246 A1, 2000 ;
反应条件
in benzene
4 h; Heating;
参考文献
Chua, Mei-Sze; Shi, Dong-Fang; Wrigley, Samantha; Bradshaw, Tracey D.; Hutchinson, Ian; Shaw, P. Nicholas; Barrett, David A.; Stanley, Lesley A.; Stevens, Malcolm F. G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 381 - 392
反应条件
toluene-4-sulfonic acid in PEG-200/400
0.0833333 h; Microwave irradiation;
参考文献
Deligeorgiev, Todor G.; Kaloyanova, Stefka; Vasilev, Aleksey; Vaquero, Juan J.
Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 11 p. 2292 - 2302
反应条件
ammonium sulfate; acetic acid; zinc in ethylene glycol dimethyl ether
reductive acetylation; 2 h; Heating;
参考文献
Kashiyama, Eiji; Hutchinson, Ian; Chua, Mei-Sze; Stinson, Sherman F.; Phillips, Lawrence R.; Kaur, Gurmeet; Sausville, Edward A.; Bradshaw, Tracey D.; Westwell, Andrew D.; Stevens, Malcolm F. G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 20 p. 4172 - 4184
反应条件
1: pyridine / 0.5 h / Heating
2: 42 percent / Zn; AcOH; ammonium sulfate / 1,2-dimethoxy-ethane / 2 h / Heating
View Scheme
参考文献
Kashiyama, Eiji; Hutchinson, Ian; Chua, Mei-Sze; Stinson, Sherman F.; Phillips, Lawrence R.; Kaur, Gurmeet; Sausville, Edward A.; Bradshaw, Tracey D.; Westwell, Andrew D.; Stevens, Malcolm F. G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 20 p. 4172 - 4184
反应条件
1: pyridine / 0.5 h / Heating
2: 42 percent / Zn; AcOH; ammonium sulfate / 1,2-dimethoxy-ethane / 2 h / Heating
View Scheme
参考文献
Kashiyama, Eiji; Hutchinson, Ian; Chua, Mei-Sze; Stinson, Sherman F.; Phillips, Lawrence R.; Kaur, Gurmeet; Sausville, Edward A.; Bradshaw, Tracey D.; Westwell, Andrew D.; Stevens, Malcolm F. G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 20 p. 4172 - 4184
反应条件
1: polyphosphoric acid / 220 °C
2: 88 percent / benzene / 4 h / Heating
View Scheme
参考文献
Chua, Mei-Sze; Shi, Dong-Fang; Wrigley, Samantha; Bradshaw, Tracey D.; Hutchinson, Ian; Shaw, P. Nicholas; Barrett, David A.; Stanley, Lesley A.; Stevens, Malcolm F. G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 381 - 392
参考文献
Brembilla,A.; Lochon,P.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1978 , vol. 286, p. 557 - 559
