1: diethyl 2-acetylaminomalonate With sodium ethanolate in ethanol
1.66667 h; Heating;
2: 1-bromomethyl-4-nitro-benzene in ethanol
20 h; Heating; Further stages.;
参考文献
Chong, Hyun-Soon; Ma, Xiang; Le, Thien; Kwamena, Baidoo; Milenic, Diane E.; Brady, Erik D.; Song, Hyun A.; Brechbiel, Martin W.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 1 p. 118 - 125