2-氨基-3,3-二苯丙酸合成路线 (共 7 条)
反应条件
hydrogenchloride; sodium hydroxide in water Hydrolysis; 18 h; Heating;
参考文献
Kanemasa; Adachi; Yamamoto; Wada
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 3 p. 681 - 687
反应条件
1: 90 percent / ethanol; H2O / 8 h / 50 °C 2: 99 percent / NaOH; hydrochloric acid / H2O / 18 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 73, # 3 p. 681 - 687
参考文献
Journal of the Chemical Society, , p. 896
参考文献
Harington; McCartney
Journal of the Chemical Society, 1929 , p. 896
反应条件
sulfuric acid in methanol; water T=25°C; Resolution of racemate;
参考文献
Bang, Eunjung; Jin, Jing Yu; Hong, Joon Hee; Kang, Jong Seong; Lee, Weontae; Lee, Wonjae
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 10 p. 3481 - 3484
反应条件
sulfuric acid in methanol; water T=25°C; Resolution of racemate;
参考文献
Bang, Eunjung; Jin, Jing Yu; Hong, Joon Hee; Kang, Jong Seong; Lee, Weontae; Lee, Wonjae
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 10 p. 3481 - 3484
反应条件
sodium carbonate in 1,4-dioxane
T=0 - 20°C; 2 h;
参考文献
Jorgensen, Malene R.; Olsen, Christian A.; Mellor, Ian R.; Usherwood, Peter N. R.; Witt, Matthias; Franzyk, Henrik; Jaroszewski, Jerzy W.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 56 - 70