1,2,3,4-四氢萘-1-乙酸乙酯合成路线 （共 5 条）
反应条件
1: 80 percent / zinc, iodine / tetrahydrofuran / 3.5 h / Heating
2: P2O5 / benzene / 2 h / Heating
View Scheme
参考文献
Miyashi,T.; Nishizawa,Y.; Fujii,Y.
Journal of the American Chemical Society, 1986 , vol. 108, p. 1617
反应条件
phosphorus pentoxide in benzene
2 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Miyashi,T.; Nishizawa,Y.; Fujii,Y.
Journal of the American Chemical Society, 1986 , vol. 108, p. 1617
反应条件
1: diethoxyphosphoryl-acetic acid ethyl ester With sodium methylate in ethanol
0.0833333 h;
2: 3,4-dihydronaphthalene-1(2H)-one in ethanol
18 h; Heating / reflux;
参考文献
BAYER HEALTHCARE AG
Patent: WO2005/16881 A1, 2005 ;
Location in patent: Page/Page column 24; 25 ;
WO 2005/016881 A1
反应条件
diisobutylaluminium hydride in hexane; toluene
T=-78 - 20°C; 12 h;
参考文献
Takeda, Momotaro; Takatsu, Keishi; Shintani, Ryo; Hayashi, Tamio
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2354 - 2367
反应条件
hydrogen; 10 palladium on activated carbon in ethanol
P=2250.23 Torr; 4 h;
参考文献
BAYER HEALTHCARE AG
Patent: WO2005/16881 A1, 2005 ;
Location in patent: Page/Page column 25 ;
WO 2005/016881 A1
