2-(2-甲氧基-苯基)-苯并噻唑合成路线 （共 15 条）
反应条件
dipotassium peroxodisulfate; potassium tert-butylate in water; dimethyl sulfoxide
T=100°C; 8 h;
参考文献
Yang, Zhiyong; Wang, Anwei; Chen, Xiang; Gui, Qingwen; Liu, Jidan; Tan, Ze; Wang, Hua; Shi, Ji-Cheng
Synlett, 2013 , vol. 24, # 12 art. no. ST-2013-W0351-L, p. 1549 - 1554
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethylene glycol dimethyl ether; water
T=150°C; Suzuki coupling; Microwave irradiationCombinatorial reaction / High throughput screening (HTS);
参考文献
Auld, Douglas S.; Zhang, Ya-Qin; Southall, Noel T.; Rai, Ganesha; Landsman, Marc; MacLure, Jennifer; Langevin, Daniel; Thomas, Craig J.; Austin, Christopher P.; Inglese, James
Journal of Medicinal Chemistry, 2009 , vol. 52, # 5 p. 1450 - 1458
参考文献
Nagaoka, Shin-ichi; Itoh, Akinori; Mukai, Kazuo; Nagashima, Umpei
Journal of Physical Chemistry, 1993 , vol. 97, # 44 p. 11385 - 11392
反应条件
1: NaOH; (n-Bu)4NBr
2: 85 percent / p-toluenesulfonic acid monohydrate / CHCl3 / 24 h / Heating
View Scheme
参考文献
Chen, Lianqing; Yang, Chuluo; Li, Suyue; Qin, Jingui
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2007 , vol. 68, # 2 p. 317 - 322
反应条件
sodium hydride
1.) THF, RT, 15 min, 2.) THF, 60 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Mettey, Yvette; Michaud, Sabine; Vierfond, Jean Michel
Heterocycles, 1994 , vol. 38, # 5 p. 1001 - 1006
