1-(4-硝基苯基)哌嗪合成路线 （共 39 条）
反应条件
1: With Amberlyst(R) 15 in dichloromethane T=20°C; 2: With ammonium hydroxide in methanol T=20°C; 1.5 h;
参考文献
Duncton, Matthew A. J.; Roffey, Jonathan R. A.; Hamlyn, Richard J.; Adams, David R.
Tetrahedron Letters, 2006 , vol. 47, # 15 p. 2549 - 2552
反应条件
tetra-(n-butyl)ammonium iodide; potassium carbonate in dimethyl sulfoxide T=120°C; Arylation; 12 h;
参考文献
Hepperle, Michael; Eckert, Jeffrey; Gala, Dinesh
Tetrahedron Letters, 1999 , vol. 40, # 31 p. 5655 - 5659
反应条件
tetra-(n-butyl)ammonium iodide; potassium carbonate in dimethyl sulfoxide T=120°C; Arylation; 12 h;
参考文献
Hepperle, Michael; Eckert, Jeffrey; Gala, Dinesh
Tetrahedron Letters, 1999 , vol. 40, # 31 p. 5655 - 5659
反应条件
in various solvent(s) T=150°C;
参考文献
Liu, Kevin G.; Robichaud, Albert J.
Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7921 - 7922
反应条件
in chloroform; acetonitrile
反应条件
potassium carbonate in dimethyl sulfoxide Arylation; Heating;
参考文献
Hepperle, Michael; Eckert, Jeffrey; Gala, Dinesh
Tetrahedron Letters, 1999 , vol. 40, # 31 p. 5655 - 5659
反应条件
1.1: macroporous polymer-supported carbonate / dimethylsulfoxide / 100 °C 1.2: macroporous polymer-supported isocyanate / CH2Cl2 / 60 °C 2.1: Amberlyst(R) 15 / CH2Cl2 / 20 °C 2.2: 94 percent / aq. NH3 / methanol / 1.5 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2549 - 2552
反应条件
potassium phosphate; copper(l) iodide in isopropyl alcohol T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 22 p. 6245 - 6249
反应条件
1.1: tri-tert-butylphosphine; palladium(II) acetate; sodium tert-butoxide / xylene / 50 °C 1.2: 100 percent / macroporous polymer-supported isocyanate / xylene / 24 h / 50 °C 2.1: Amberlyst(R) 15 / CH2Cl2 / 20 °C 2.2: 94 percent / aq. NH3 / methanol / 1.5 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2549 - 2552
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 6, p. 211,218
