1-(4-硝基苯基)哌嗪合成路线 （共 39 条）
反应条件
triethylamine in palladium monocarbide; ethanol; dichloromethane
反应条件
1: Et3N / CH2Cl2 / 20 °C 2: H2 / 10 percent Pd/C / methanol / 20 °C / 1500.12 Torr View Scheme
参考文献
Archiv der Pharmazie, , vol. 333, # 8 p. 267 - 274
反应条件
N-ethyl-N,N-diisopropylamine in 1,4-dioxane
参考文献
Chen, Li; Ding, Qingjie; Gillespie, Paul; Kim, Kyungjin; Lovey, Allen John; McComas, Warren William; Mullin JR., John Guilfoye; Perrotta, Agostino
Patent: US2002/151554 A1, 2002 ;
反应条件
triethylamine in dichloromethane; water
参考文献
Harnett, Jeremiah; Auguet, Michel
Patent: US2003/105107 A1, 2003 ;
反应条件
in dichloromethane; ethyl acetate
参考文献
Booth, Richard John; Dobrusin, Ellen Myra; Josyula, Vara Prasad Venkata Nagendra; McNamara, Dennis Joseph; Toogood, Peter Laurence
Patent: US2003/73668 A1, 2003 ;
US 20030073668 A1
反应条件
triethylamine in acetonitrile 12 h; Reflux;
参考文献
F2G LTD
Patent: WO2009/130481 A1, 2009 ;
Location in patent: Page/Page column 136-137 ;
反应条件
potassium carbonate in butanone T=80°C; 24 h;
参考文献
Sukalovic, Vladimir; Zlatovic, Mario; Andric, Deana; Roglic, Goran; Kostic-Rajacic, Sladjana; Soskic, Vukic
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 3 p. 145 - 152
反应条件
1: Et3N / CH2Cl2 / 2 h / 0 °C 2: CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Katz, H. E.; Schilling, M. L.
Journal of the American Chemical Society, 1989 , vol. 111, # 19 p. 7554 - 7557
反应条件
triethylamine in dichloromethane
T=0°C; 2 h;
参考文献
Katz, H. E.; Schilling, M. L.
Journal of the American Chemical Society, 1989 , vol. 111, # 19 p. 7554 - 7557
反应条件
potassium carbonate in dichloromethane
参考文献
Chen, Li; Ding, Qingjie; Gillespie, Paul; Kim, Kyungjin; Lovey, Allen John; McComas, Warren William; Mullin JR., John Guilfoye; Perrotta, Agostino
Patent: US2002/151554 A1, 2002 ;
