2-羟基-4-甲氧基苯甲酸乙酯合成路线 （共 27 条）
反应条件
2: pyridine; KOH / ansliessend Behandeln mit wss.Essigsaeure 3: acetic acid; aqueous hydrochloric acid View Scheme
参考文献
Ollis; Weight
Journal of the Chemical Society, 1952 , p. 3826,3830
反应条件
1: sodium benzoate / 190 °C 2: acetic acid; aqueous hydrochloric acid / Einleiten von Chlorwasserstoff View Scheme
参考文献
Da Re; Verlicchi
Annali di Chimica (Rome, Italy), 1956 , vol. 46, p. 910,917
反应条件
phenylacetic acid sodium salt T=180 - 190°C; 8 h;
参考文献
Carrara, Maria; Capolongo, Francesca; Cima, Lorenzo; Fabbri, Giuseppina; Rampa, Angela; et al.
Collection of Czechoslovak Chemical Communications, 1991 , vol. 56, # 11.1 p. 2402 - 2405
反应条件
(PhCH2CO)2O T=180°C;
参考文献
Heilbron et al.
Journal of the Chemical Society, 1936 , p. 295,299, 300
Journal of the Chemical Society, 1934 , p. 1311,1581
反应条件
4-nitrobenzoic acid potassium salt
8 h; Heating;
参考文献
Recanatini; Valenti; Da Re; Giusti
Archiv der Pharmazie, 1989 , vol. 322, # 5 p. 257 - 261
反应条件
1: (CH3CO)2O, CH3COONa
2: 87 percent / conc. HCl / 7 h / 70 °C
View Scheme
参考文献
Zammattio, F.; Brion, J. D.; Belachmi, L.; Le Baut, G.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 2013 - 2019
反应条件
1: 70 percent / sodium p-fluorobenzoate
2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C
3: 90 percent / benzene / 48 h / Ambient temperature
View Scheme
参考文献
Valenti; Recanatini; da Re; Cima; Giusti
Archiv der Pharmazie, 1983 , vol. 316, # 5 p. 421 - 426
反应条件
1: 70 percent / sodium p-fluorobenzoate
2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C
3: 85 percent / benzene / 48 h / Ambient temperature
View Scheme
参考文献
Valenti; Recanatini; da Re; Cima; Giusti
Archiv der Pharmazie, 1983 , vol. 316, # 5 p. 421 - 426
反应条件
1: 70 percent / sodium p-fluorobenzoate
2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C
3: 80 percent / benzene / 48 h / Ambient temperature
View Scheme
参考文献
Valenti; Recanatini; da Re; Cima; Giusti
Archiv der Pharmazie, 1983 , vol. 316, # 5 p. 421 - 426
反应条件
1: 70 percent / sodium p-fluorobenzoate
2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C
3: 85 percent / benzene / 48 h / Ambient temperature
View Scheme
参考文献
Valenti; Recanatini; da Re; Cima; Giusti
Archiv der Pharmazie, 1983 , vol. 316, # 5 p. 421 - 426
