1-(4-氯苯基)-2-硝基苯合成路线 （共 31 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in water; N,N-dimethyl-formamide
T=80°C; 5 h; Inert atmosphere;
参考文献
Gao, Hongyin; Xu, Qing-Long; Yousufuddin, Muhammed; Ess, Daniel H.; Kuerti, Laszlo
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2701 - 2705
Angew. Chem., 2014 , vol. 53, # 10 p. 2739 - 2743,5
反应条件
1: (3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)(4-chlorophenyl)bis(naphthalen-2-ylmethyl)germane With Cu(BF4)2 in methanol; acetonitrile
2 h; Irradiation;
2: 1-bromonitrobenzene With copper(l) iodide; tetrabutyl ammonium fluoride; tris-(o-tolyl)phosphine; dichloro bis(acetonitrile) palladium(II) in N,N-dimethyl-formamide
T=120°C; 16 h; Further stages.;
参考文献
Spivey, Alan C.; Tseng, Chih-Chung; Hannah, Joseph P.; Gripton, Christopher J. G.; De Fraine, Paul; Parr, Nigel J.; Scicinski, Jan J.
Chemical Communications, 2007 , # 28 p. 2926 - 2928
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=150°C; Suzuki-Miyaura cross-coupling reaction; 0.166667 h; microwave irradiation;
参考文献
Appukkuttan, Prasad; Van Der Eycken, Erik; Dehaen, Wim
Synlett, 2005 , # 1 art. no. G33904ST, p. 127 - 133
反应条件
bis(acetylacetonato) palladium; copper(l) iodide; 1,10-phenanthroline in 1-methyl-pyrrolidin-2-one; quinoline
T=50 - 190°C; P=4125.41 Torr; 0.25 h; Inert atmosphereMicrowave irradiation;
参考文献
Goossen, Lukas J.; Linder, Bettina Zimmermanns Christophe; Rodriguez, Nuria; Lange, Paul P.; Hartung, Jens
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 16 p. 2667 - 2674
反应条件
5-palladium/activated carbon in methanol
T=25°C; Suzuki-Miyaura reaction; 12 h;
参考文献
Felpin, Francois-Xavier; Fouquet, Eric; Zakri, Cecile
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 4 p. 649 - 655
反应条件
sodium methylate in 1,4-dioxane
T=100°C; Suzuki-Miyaura Coupling; 25 h; Schlenk technique;
参考文献
Santra, Subhankar; Hota, Pradip Kumar; Bhattacharyya, Rangeet; Bera, Parthasarathi; Ghosh, Prasenjit; Mandal, Swadhin K.
ACS Catalysis, 2013 , vol. 3, # 12 p. 2776 - 2789
反应条件
1: ortho-nitrobenzoic acid With cupric(II) carbonate in various solvent(s)
T=120°C; 0.5 h;
2: 1-chloro-4-bromobenzene With triphenylphosphine; palladium acetylacetonate in various solvent(s)
T=120°C; 24 h; Further stages.;
参考文献
Goossen, Lukas J.; Rodriguez, Nuria; Melzer, Bettina; Linder, Christophe; Deng, Guojun; Levy, Laura M.
Journal of the American Chemical Society, 2007 , vol. 129, # 15 p. 4824 - 4833
反应条件
tetrabutylammomium bromide; palladium diacetate in N-methyl-acetamide; water; ethyl acetate
参考文献
Murase, Seiichiro; Nagao, Kazumasa; Sugimoto, Kazunori; Ishigaki, Takeshi; Ogawa, Takafumi
Patent: US2009/96356 A1, 2009 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium tert-butylate in water; tert-butyl alcohol
T=160°C; Suzuki coupling; P=7500.75 Torr; 0.25 h; Microwave irradiation;
参考文献
Glasnov, Toma N.; Kappe, C. Oliver
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 17 p. 3089 - 3097
反应条件
tetrakis(triphenylphosphine) palladium(0); copper(I) thiophene-2-carboxylate in methanol
T=22°C; 2 h; chemoselective reaction;
参考文献
Creech, Gardner S.; Kwon, Ohyun
Chemical Science, 2013 , vol. 4, # 6 p. 2670 - 2674
