1-(4-氯苯基)-2-硝基苯合成路线 （共 31 条）
反应条件
2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; N,N-dimethyl-aniline; silver carbonate; palladium dichloride
T=150°C; 2 h;
参考文献
Wang, Zhiyong; Ding, Qiuping; He, Xiaodan; Wu, Jie
Tetrahedron, 2009 , vol. 65, # 24 p. 4635 - 4638
反应条件
P(t-Bu)2Me*HBF4; palladium diacetate; potassium carbonate; 2,2,2-trimethylacetic acid in 1,3,5-trimethyl-benzene
T=125°C; 5 h; Inert atmosphere; regioselective reaction;
参考文献
Caron, Laurence; Campeau, Louis-Charles; Fagnou, Keith
Organic Letters, 2008 , vol. 10, # 20 p. 4533 - 4536
反应条件
sulfuric acid; nitric acid
T=65°C;
参考文献
Bradsher; Wissow
Journal of the American Chemical Society, 1946 , vol. 68, p. 404
反应条件
1: 63 percent / fuming HNO3; urea
2: 88 percent / aq. NaHCO3 / Pd(Ph3P)4 / dimethylformamide / 0.17 h / 150 °C / microwave irradiation
View Scheme
参考文献
Appukkuttan, Prasad; Van Der Eycken, Erik; Dehaen, Wim
Synlett, 2005 , # 1 art. no. G33904ST, p. 127 - 133
反应条件
1: bis(4-chlorophenyl)borinic acid With sodium hydroxide in 1,4-dioxane; water
T=18 - 22°C; 1.1 h;
2: With triphenylphosphine in 1,4-dioxane; water
T=18 - 22°C; 0.5 h;
3: 1-chloro-2-nitro-benzene With dichloro bis(acetonitrile) palladium(II) in 1,4-dioxane; water
T=100°C; P=2775.28 Torr; 11.5 h; Product distribution / selectivity;
参考文献
BASF AKTIENGESELLSCAHFT
Patent: WO2006/92429 A1, 2006 ;
Location in patent: Page/Page column 9-10 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium hydroxide in tetrahydrofuran; water
T=160°C; Suzuki coupling; 0.25 h; Microwave irradiation;
参考文献
Glasnov, Toma N.; Kappe, C. Oliver
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 17 p. 3089 - 3097
反应条件
chlorine; tin tetraiodide
参考文献
Shih; Hey; Williams
Journal of the Chemical Society, 1958 , p. 1885,1887
参考文献
Bradsher; Wissow
Journal of the American Chemical Society, 1946 , vol. 68, p. 404
参考文献
I.G.Farbenind.
Patent: DE748375 , 1939 ;
DRP/DRBP Org.Chem.
反应条件
triethyl phosphite
T=210°C; Cadogan cyclization; 0.166667 h; microwave irradiation;
参考文献
Appukkuttan, Prasad; Van Der Eycken, Erik; Dehaen, Wim
Synlett, 2005 , # 1 art. no. G33904ST, p. 127 - 133
