2-甲氧基-4-硝基苯甲酰胺合成路线 （共 4 条）
反应条件
ammonium hydroxide in methanol
10 h; Ambient temperature;
参考文献
Takeuchi, Yasuo; Oda, Toshiaki; Chang, Ming-Rong; Okamoto, Yoko; Ono, Junko; Oda, Yoko; Harada, Kyoko; Hashigaki, Kuniko; Yamato, Masatoshi
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 2 p. 406 - 411
参考文献
Clinton et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 2290,2291
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 80 °C / Inert atmosphere
2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Inert atmosphere
3: ammonium hydroxide / dichloromethane / Inert atmosphere
View Scheme
参考文献
Adler, Marc J.; Hamilton, Andrew D.
Journal of Organic Chemistry, 2011 , vol. 76, # 17 p. 7040 - 7047
反应条件
1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Inert atmosphere
2: ammonium hydroxide / dichloromethane / Inert atmosphere
View Scheme
参考文献
Adler, Marc J.; Hamilton, Andrew D.
Journal of Organic Chemistry, 2011 , vol. 76, # 17 p. 7040 - 7047
