1: acetone; KOH-solution / Faellen der Loesung mit Salzsaeure 2: ammonia; zinc dust / Ansaeuern der Loesung und Kochen des Reduktionsprodukts mit Essigsaeureanhydrid 3: alkali 4: zinc dust; NaOH-solution 5: potash View Scheme

暂无反应条件数据

sodium hydroxide 0.0833333 h;

暂无反应条件数据

1: acetone; KOH-solution / Faellen der Loesung mit Salzsaeure 2: ammonia; zinc dust / Ansaeuern der Loesung und Kochen des Reduktionsprodukts mit Essigsaeureanhydrid 3: alkali 4: zinc dust; NaOH-solution 5: potash 6: acetic acid anhydride View Scheme

acetic anhydride in dimethyl sulfoxide T=100°C; 0.25 h;

1: 68 percent / triethylamine / tetrahydrofuran / 0.5 h / 25 °C 2: 91 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / dimethylformamide / 3 h / -15 °C 3: 82 percent / diethyl ether / 0.25 h / 0 °C 4: 90 percent / bromine / acetic acid / 3 h / Ambient temperature 5: 22 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / benzene 6: 92 percent / boron tribromide / hexane; CH2Cl2 / 0.5 h / Heating 7: 90 percent / sodium ethoxide / ethanol / 0.5 h / Ambient temperature 8: 89 percent / acetic anhydride / dimethylsulfoxide / 0.25 h / 100 °C View Scheme

1: 2) dil. aq. hydrochloric acid / 1) diethyl ether, reflux, 3 h, 2) 25 deg C, overnight 2: 68 percent / triethylamine / tetrahydrofuran / 0.5 h / 25 °C 3: 91 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / dimethylformamide / 3 h / -15 °C 4: 82 percent / diethyl ether / 0.25 h / 0 °C 5: 90 percent / bromine / acetic acid / 3 h / Ambient temperature 6: 22 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / benzene 7: 92 percent / boron tribromide / hexane; CH2Cl2 / 0.5 h / Heating 8: 90 percent / sodium ethoxide / ethanol / 0.5 h / Ambient temperature 9: 89 percent / acetic anhydride / dimethylsulfoxide / 0.25 h / 100 °C View Scheme

1: 82 percent / diethyl ether / 0.25 h / 0 °C 2: 90 percent / bromine / acetic acid / 3 h / Ambient temperature 3: 22 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / benzene 4: 92 percent / boron tribromide / hexane; CH2Cl2 / 0.5 h / Heating 5: 90 percent / sodium ethoxide / ethanol / 0.5 h / Ambient temperature 6: 89 percent / acetic anhydride / dimethylsulfoxide / 0.25 h / 100 °C View Scheme

1: 90 percent / bromine / acetic acid / 3 h / Ambient temperature 2: 22 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / benzene 3: 92 percent / boron tribromide / hexane; CH2Cl2 / 0.5 h / Heating 4: 90 percent / sodium ethoxide / ethanol / 0.5 h / Ambient temperature 5: 89 percent / acetic anhydride / dimethylsulfoxide / 0.25 h / 100 °C View Scheme