2-氨基-5-甲氧基苯硫酚合成路线 （共 29 条）
反应条件
1: aqueous NaOH-solution 2: sodium acetate; acetic acid View Scheme
参考文献
Ast; Bogert
Recueil des Travaux Chimiques des Pays-Bas, 1935 , vol. 54, p. 917,924
参考文献
Boehringer Ingelheim GmbH
Patent: US4328235 A1, 1982 ;
参考文献
Taisho Pharmaceutical Co., Ltd.
Patent: US4150240 A1, 1979 ;
反应条件
oxygen in dimethyl sulfoxide; chlorobenzene T=140°C; P=760.051 Torr; 16 h; Sealed tube;
参考文献
Liao, Yunfeng; Qi, Hongrui; Chen, Shanping; Jiang, Pengcheng; Zhou, Wang; Deng, Guo-Jun
Organic Letters, 2012 , vol. 14, # 23 p. 6004 - 6007
反应条件
1: H2O / 24 h / 5 °C 2: 48percent hydrobromic acid View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 51, # 9 p. 2116 - 2128,1822 - 1831
反应条件
in water T=5°C; 24 h; Yield given;
参考文献
El'tsov, A. V.; Kukushkin, V. Yu.; Bykova, L. M.
J. Gen. Chem. USSR (Engl. Transl.), 1981 , vol. 51, # 9 p. 2116 - 2128,1822 - 1831
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium hydrogencarbonate in acetonitrile T=0°C; Reflux;
参考文献
Zhang, Li-Qiu; Guan, Li-Ping; Wei, Cheng-Xi; Deng, Xian-Qing; Quan, Zhe-Shan
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 3 p. 326 - 331
反应条件
(Omim)(NO3) T=20°C; 0.25 h; Green chemistry; Mechanism;
参考文献
Sharifi, Ali; Abaee, M. Saeed; Rouzgard, Mahdiyeh; Mirzaei, Mojtaba
Synthetic Communications, 2013 , vol. 43, # 15 p. 2079 - 2089
参考文献
SHANGHAI DE NOVO PHARMATECH CO LTD.; GAO, Daxin; YANG, Heping; YU, Yajun
Patent: WO2013/91502 A1, 2013 ;
Location in patent: Page/Page column 28; 29 ;
参考文献
Takahashi et al.
Yakugaku Zasshi, 1951 , vol. 71, p. 41,43
Chem.Abstr., 1951 , p. 7109
