反应条件
1: (5S)-5-(aminomethyl)-3-(3-fluoro-4-iodophenyl)-1,3-oxazolidin-2-on With triethylamine in dichloromethane
T=25°C;
2: acetic anhydride With 4-(N,N-dimethlyamino)pyridine in dichloromethane
T=0 - 5°C; 2 h; Inert atmosphere;
参考文献
Chen, Shili; Lou, Rongliang; Wu, Yusheng; Zhou, Jiacheng; Hanselmann, Roger
Patent: US2010/234615 A1, 2010 ;
Location in patent: Page/Page column 37-38 ;