1: aqueous KOH 2: methanol; diethyl ether View Scheme

potassium hydroxide Kupfer-Gefaess;

potassium hydroxide

T=230°C; 1 h;

trifluoroacetic acid T=5°C; 0.25 h;

2: 63 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 18 h / 20 °C 3: 60 percent / H2 / 10percent Pd/C / ethanol / 3 h / 2585.7 Torr 4: 97 percent / I2, NaHCO3 / ethanol; H2O / 1.5 h / 20 °C 5: 93 percent / H2, sodium acetate / 10percent Pd/C / ethanol / 3 h / 2327.2 Torr 6: 80 percent / trifluoroacetic acid / 0.25 h / 5 °C View Scheme

1: 1.) NaNO2, acetic acid, 2.) Zn, acetic acid, sodium acetate / 1.) H2O, 5 deg C, 15 h, 2.) 75 deg C, 1.5 h 3: 63 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 18 h / 20 °C 4: 60 percent / H2 / 10percent Pd/C / ethanol / 3 h / 2585.7 Torr 5: 97 percent / I2, NaHCO3 / ethanol; H2O / 1.5 h / 20 °C 6: 93 percent / H2, sodium acetate / 10percent Pd/C / ethanol / 3 h / 2327.2 Torr 7: 80 percent / trifluoroacetic acid / 0.25 h / 5 °C View Scheme

1: 93 percent / H2, sodium acetate / 10percent Pd/C / ethanol / 3 h / 2327.2 Torr 2: 80 percent / trifluoroacetic acid / 0.25 h / 5 °C View Scheme

1: 97 percent / I2, NaHCO3 / ethanol; H2O / 1.5 h / 20 °C 2: 93 percent / H2, sodium acetate / 10percent Pd/C / ethanol / 3 h / 2327.2 Torr 3: 80 percent / trifluoroacetic acid / 0.25 h / 5 °C View Scheme

1: 60 percent / H2 / 10percent Pd/C / ethanol / 3 h / 2585.7 Torr 2: 97 percent / I2, NaHCO3 / ethanol; H2O / 1.5 h / 20 °C 3: 93 percent / H2, sodium acetate / 10percent Pd/C / ethanol / 3 h / 2327.2 Torr 4: 80 percent / trifluoroacetic acid / 0.25 h / 5 °C View Scheme