4-硝基-1,3-二苯基-1-丁酮合成路线 （共 9 条）
反应条件
1.1: KOH / methanol; tetrahydrofuran / 1 h / 20 °C 1.2: 73 percent / H2SO4 / tetrahydrofuran / 1 h / 20 °C 2.1: 0.31 g / AcOH; NH4OAc / 1 h / 100 °C 3.1: 79 percent / aq. HCl; aq. NaNO3 / ethanol / 0 - 20 °C View Scheme
参考文献
Hall, Michael J.; McDonnell, Shane O.; Killoran, John; O'Shea, Donal F.
Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5571 - 5578
反应条件
1.1: KOH / methanol; tetrahydrofuran / 1 h / 20 °C 1.2: 73 percent / H2SO4 / tetrahydrofuran / 1 h / 20 °C 2.1: 0.31 g / AcOH; NH4OAc / 1 h / 100 °C View Scheme
参考文献
Rogers
Journal of the Chemical Society, 1943 , p. 596
参考文献
Rogers
Journal of the Chemical Society, 1943 , p. 596
反应条件
bromine; sodium methylate
参考文献
Kohler
Journal of the American Chemical Society, 1916 , vol. 38, p. 896
Journal of the American Chemical Society, 1924 , vol. 46, p. 510
参考文献
Kohler
Journal of the American Chemical Society, 1916 , vol. 38, p. 896
Journal of the American Chemical Society, 1924 , vol. 46, p. 510
反应条件
hydrogenchloride; zinc in N,N-dimethyl-formamide
T=80°C; 1.5 h;
参考文献
Liang, Yongjiu; Dong, Dewen; Lu, Yumei; Wang, Yan; Pan, Wei; Chai, Yanyan; Liu, Qun
Synthesis, 2006 , # 19 p. 3301 - 3304
反应条件
1.1: triethylamine / CH2Cl2 / 168 h / -30 °C
1.2: 88 percent / water / light petroleum; CH2Cl2
2.1: 85 percent / NH4F / methanol / 0.5 h / 0 °C
View Scheme
参考文献
Tishkov, Alexander A.; Kozintsev, Anton V.; Lyapkalo, Il'ya M.; Ioffe, Sema L.; Kachala, Vadim V.; Strelenko, Yuri A.; Tartakovsky, Vladimir A.
Tetrahedron Letters, 1999 , vol. 40, # 27 p. 5075 - 5078
反应条件
chloroform; bromine
lower-melting form;
参考文献
Kohler
Journal of the American Chemical Society, 1924 , vol. 46, p. 512
参考文献
Kohler
Journal of the American Chemical Society, 1916 , vol. 38, p. 896
Journal of the American Chemical Society, 1924 , vol. 46, p. 510
