(S)-1-苯基-1,2-乙二胺合成路线 （共 20 条）
反应条件
1: ethanol; water 2: sodium carbonate / isopropyl alcohol View Scheme
参考文献
Sadhukhan, Arghya; Sahu, Debashis; Ganguly, Bishwajit; Khan, Noor-Ul H.; Kureshy, Rukhsana I.; Abdi, Sayed H.R.; Suresh; Bajaj, Hari C.
Chemistry - A European Journal, 2013 , vol. 19, # 42 p. 14224 - 14232
反应条件
1: sodium tetrahydroborate; iodine / tetrahydrofuran / 19 h / 0 °C / |Reflux 2: triethylamine / dimethyl sulfoxide / 2 h / 100 °C / |Irradiation View Scheme
参考文献
Wang, Hong-Yu; Chai, Zhuo; Zhao, Gang
Tetrahedron, 2013 , vol. 69, # 25 p. 5104 - 5111
反应条件
trifluoroacetic acid in dichloromethane
24 h;
参考文献
Wang, Hong-Yu; Chai, Zhuo; Zhao, Gang
Tetrahedron, 2013 , vol. 69, # 25 p. 5104 - 5111
反应条件
hydrogen; palladium on activated charcoal in methanol
P=760 Torr; 2 h;
参考文献
Rama Rao; Gurjar; Kaiwar
Tetrahedron Asymmetry, 1992 , vol. 3, # 7 p. 859 - 862
反应条件
hydrogenchloride; methanol; hydrogen; palladium on activated charcoal
P=4654.3 Torr; 24 h; Ambient temperature; Yield given;
参考文献
Hsiao, Yi; Hegedus, Louis S.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3586 - 3591
反应条件
1: 98 percent / Et3N / CH2Cl2 / 0.33 h / 20 °C
2: 78 percent / NaN3, nBu4NBr / toluene; H2O / 85 - 90 °C
3: H2, MeOH-HCl / Pd/C / 24 h / 4654.3 Torr / Ambient temperature
View Scheme
参考文献
Hsiao, Yi; Hegedus, Louis S.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3586 - 3591
反应条件
1: 97 percent / LiAlH4 / tetrahydrofuran / Heating
2: 90 percent / NaHCO3 / CH2Cl2 / 20 °C
3: 98 percent / Et3N / CH2Cl2 / 0.33 h / 20 °C
4: 78 percent / NaN3, nBu4NBr / toluene; H2O / 85 - 90 °C
5: H2, MeOH-HCl / Pd/C / 24 h / 4654.3 Torr / Ambient temperature
View Scheme
参考文献
Hsiao, Yi; Hegedus, Louis S.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3586 - 3591
反应条件
1: 90 percent / NaHCO3 / CH2Cl2 / 20 °C
2: 98 percent / Et3N / CH2Cl2 / 0.33 h / 20 °C
3: 78 percent / NaN3, nBu4NBr / toluene; H2O / 85 - 90 °C
4: H2, MeOH-HCl / Pd/C / 24 h / 4654.3 Torr / Ambient temperature
View Scheme
参考文献
Hsiao, Yi; Hegedus, Louis S.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3586 - 3591
反应条件
1: 78 percent / NaN3, nBu4NBr / toluene; H2O / 85 - 90 °C
2: H2, MeOH-HCl / Pd/C / 24 h / 4654.3 Torr / Ambient temperature
View Scheme
参考文献
Hsiao, Yi; Hegedus, Louis S.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3586 - 3591
反应条件
1: NaN3 / dimethylformamide / 8 h / 80 °C
2: TPP, DIAD / tetrahydrofuran / 8 h / Ambient temperature
3: NH2NH2 / ethanol / 1 h / Heating
4: H2 / Pd/C / methanol / 2 h / 760 Torr
View Scheme
参考文献
Rama Rao; Gurjar; Kaiwar
Tetrahedron Asymmetry, 1992 , vol. 3, # 7 p. 859 - 862
