4-(2-苯并噻唑基)苯胺合成路线 （共 31 条）
反应条件
1: phosphorus pentachloride / chlorobenzene / 100 °C 2: hydrogenchloride; iron / methanol; water / 7 h / 90 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 14 p. 6391 - 6402
反应条件
n-butyllithium 1.) THF, hexane, -78 deg C, 20 min, 2.) THF, hexane, a) -78 deg C, 1 h, b) 23 deg C, 12 h; Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 37, # 2 p. 775 - 782
参考文献
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, , vol. 286, p. 557 - 559
反应条件
sulfuric acid 1 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 83 - 94
反应条件
sodium perborate; acetic acid; potassium bromide T=20°C; 22 h;
参考文献
Karlsson, H. Jonas; Bergqvist, Mattias H.; Lincoln, Per; Westman, Gunnar
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 9 p. 2369 - 2384
反应条件
potassium carbonate in dimethyl sulfoxide
T=100°C; 16 h;
参考文献
UNIVERSITY OF PITTSBURGH
Patent: US2003/236391 A1, 2003 ;
Location in patent: Page 16 ;
反应条件
potassium carbonate in dimethyl sulfoxide
参考文献
Klunk, William E.; Mathis JR., Chester A.; Wang, Yanming
Patent: US2002/133019 A1, 2002 ;
反应条件
iodine cloride; acetic acid
T=25°C; 1.5 h;
参考文献
Shi, Dong-Fang; Bradshaw, Tracey D.; Wrigley, Samantha; McCall, Carol J.; Lelieveld, Peter; Fichtner, Iduna; Stevens, Malcolm F. G.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 17 p. 3375 - 3384
反应条件
acetic anhydride in benzene
参考文献
Cancer Research Campaign Technology Limited
Patent: US6034246 A1, 2000 ;
