反应条件
1.1: 78 percent / KOH / dimethylsulfoxide / 16 h / 80 °C
2.1: Mg; mercury(II) chloride / diethyl ether / 0.5 h / Heating
2.2: 78 percent / diethyl ether / 0.33 h / -80 °C
3.1: 86 percent / imidazole / dimethylformamide / 24 h / 20 °C
4.1: n-BuLi / tetrahydrofuran / 0.33 h / -80 °C
4.2: 68 percent / HMPA / tetrahydrofuran / 0 °C
5.1: 99 percent / nBu4NF / tetrahydrofuran / 3 h / 45 °C
View Scheme
参考文献
Caijo, Frederic; Mosset, Paul; Gree, Rene; Audinot-Bouchez, Valerie; Boutin, Jean; Renard, Pierre; Caignard, Daniel-Henri; Dacquet, Catherine
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4421 - 4426
