反应条件
1: 1.) 6M NaOH / 1.) EtOH, room temperature, 1.5 h, 2.) dioxane, reflux, 1.5 h
2: 36 percent / α-chymotrypsin, NH4OAc, pH 6.9, 1 M NH4OH / dimethylformamide; H2O / 2 h / Ambient temperature
3: 85 percent / 5M HCl / 3.5 h / Heating
View Scheme
参考文献
Cooper, Margaret S.; Seton, Alison W.; Stevens, Malcolm F. G.; Westwell, Andrew D.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 21 p. 2613 - 2616
