1-溴-3-邻苯二甲酰亚氨基-2-丙烷酮合成路线 （共 13 条）
反应条件
sodium hydride 1.) DMF, 1 h, 2.) 16 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Leeper, Finian J.; Rock, Martin
Journal of Fluorine Chemistry, 1991 , vol. 51, # 3 p. 381 - 396
参考文献
Gabriel
Chemische Berichte, 1911 , vol. 44, p. 1910
反应条件
Dess-Martin periodane in dichloromethane
T=20°C; Dess-Martin oxidation; 0.5 h; chemoselective reaction;
参考文献
Pace, Vittorio; Holzer, Wolfgang
Tetrahedron Letters, 2012 , vol. 53, # 38 p. 5106 - 5109
反应条件
bromine in acetic acid
T=70°C; 1.16667 h;
参考文献
Han, Minsoo; Nam, Kee Dal; Shin, Dongyun; Jeong, Nakcheol; Hahn, Hoh-Gyu
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 4 p. 518 - 530
参考文献
Perumal, Senthil K.; Pratt
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4778 - 4785
反应条件
dichloromethane; benzene
unter Kuehlung und anschliessenden Behandeln mit wss.Bromwasserstoffsaeure;
参考文献
Jones et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 4526,4528
反应条件
1.1: ethyl chloroformate; triethylamine / tetrahydrofuran / -20 - -10 °C
1.2: 69 percent / tetrahydrofuran; diethyl ether / 5 - 20 °C
2.1: 73 percent / aq. HBr
View Scheme
参考文献
Perumal, Senthil K.; Pratt
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4778 - 4785
参考文献
Abbott Laboratories
Patent: US6294573 B1, 2001 ;
US 6294573 B1
反应条件
Yield given. Multistep reaction;
参考文献
Chang, Chi K.; Koo, Myoung Seo; Ward, Brian
Journal of the Chemical Society, Chemical Communications, 1982 , # 13 p. 716 - 719
反应条件
1: water; hydrogen bromide / chloroform / 0.5 h / 0 °C
2: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C
View Scheme
参考文献
Pace, Vittorio; Holzer, Wolfgang
Tetrahedron Letters, 2012 , vol. 53, # 38 p. 5106 - 5109
