1: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 80 °C / Inert atmosphere 2: water; sodium hydroxide / ethanol / 3 h / 50 °C 3: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 3 h / Reflux 4: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere 5: palladium 10 on activated carbon; hydrogen / ethanol / 15 h / 2585.81 Torr View Scheme

1: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 80 °C / Inert atmosphere 2: water; sodium hydroxide / ethanol / 3 h / 50 °C View Scheme