8-氟-Alpha-四氢萘酮合成路线 (共 5 条)
反应条件
1: With NOBF4 in acetone T=-20°C; 1.25 h; 2: in toluene Schiemann reaction; 0.25 h; Heating;
参考文献
Nguyen, Phong; Corpuz, Evelyn; Heidelbaugh, Todd M.; Chow, Ken; Garst, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10195 - 10198
反应条件
sodium hydroxide; BF3.OEt2 in dichloromethane; chloroform; ethyl acetate
反应条件
1: KMnO4; aq. MgSO4 / acetone 2: aq. NaOH / ethanol / Heating 3: NOBF4 / 1,2-dichloro-benzene / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 8 p. 2281 - 2284
反应条件
1: aq. NaOH / ethanol / Heating 2: NOBF4 / 1,2-dichloro-benzene / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 8 p. 2281 - 2284
反应条件
1: pyridine / 20 °C 2: KMnO4; aq. MgSO4 / acetone 3: aq. NaOH / ethanol / Heating 4: NOBF4 / 1,2-dichloro-benzene / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 8 p. 2281 - 2284