7-氨基-2,3-二氢-1-茚酮合成路线 （共 8 条）
反应条件
hydrogenchloride in ethanol; water T=70°C; 3 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2006/21544 A1, 2006 ;
Location in patent: Page/Page column 36-37 ;
WO 2006/021544 A1
反应条件
1: 17 g / ethanol / 16 h / 20 °C 2: 14 g / potassium permanganate; MgSO4 / acetone; H2O / 16 h / 20 °C 3: 91 percent / aq. HCl / 3 h / 90 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 26 p. 10195 - 10198
反应条件
1: 14 g / potassium permanganate; MgSO4 / acetone; H2O / 16 h / 20 °C 2: 91 percent / aq. HCl / 3 h / 90 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 26 p. 10195 - 10198
反应条件
tert.-butylnitrite; copper dichloride in acetonitrile T=65°C; 0.166667 h;
参考文献
Nguyen, Phong; Corpuz, Evelyn; Heidelbaugh, Todd M.; Chow, Ken; Garst, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10195 - 10198
反应条件
1: With hydrogenchloride; sodium nitrite in water; acetic acid T=0°C; 0.0833333 h; 2: With potassium iodide in water; acetic acid T=60°C; 1 h;
参考文献
Nguyen, Phong; Corpuz, Evelyn; Heidelbaugh, Todd M.; Chow, Ken; Garst, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10195 - 10198
反应条件
1: nitrosonium tetrafluoroborate / acetone / -15 °C 2: 0.25 g / toluene / 5.5 h / 84 °C View Scheme
参考文献
Nguyen, Phong; Corpuz, Evelyn; Heidelbaugh, Todd M.; Chow, Ken; Garst, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10195 - 10198
反应条件
1: With hydrogen bromide; sodium nitrite in ethanol; water T=0°C; 0.25 h; 2: With hydrogen bromide; copper(I) bromide in ethanol; water T=95°C; Sandmeyer-type reaction; 0.25 h;
参考文献
Nguyen, Phong; Corpuz, Evelyn; Heidelbaugh, Todd M.; Chow, Ken; Garst, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10195 - 10198
反应条件
tert.-butylnitrite; copper(ll) bromide Title compound not separated from byproducts;
参考文献
Nguyen, Phong; Corpuz, Evelyn; Heidelbaugh, Todd M.; Chow, Ken; Garst, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 26 p. 10195 - 10198
