(R)-(-)-1,3-丁二醇合成路线 （共 27 条）
反应条件
lithium aluminium tetrahydride in diethyl ether 1 h; Ambient temperature;
参考文献
Mori, Kenji; Miyake, Masahiro
Tetrahedron, 1987 , vol. 43, # 10 p. 2229 - 2240
反应条件
lt;((R)-(1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine))RuCl2gt;2NEt3; hydrogen in methanol T=50°C; P=38000 Torr; 24 h;
参考文献
Shao, Liming; Takeuchi, Kasumi; Ikemoto, Makoto; Kawai, Toshiyasu; Ogasawara, Masamichi; et al.
Journal of Organometallic Chemistry, 1992 , vol. 435, # 1.2 p. 133 - 147
反应条件
hydrogen; C52H53BN2P2Ru in tetrahydrofuran T=80°C; P=37503.8 Torr; 16 h; Product distribution / selectivity;
参考文献
US2010/63294 A1, ;
Page/Page column 17 ;
反应条件
hydrogen; palladium dihydroxide in ethyl acetate
参考文献
Hungerbuehler, Ernst von; Seebach, Dieter; Wasmuth, Daniel
Helvetica Chimica Acta, 1981 , vol. 64, # 5 p. 1467 - 1487
反应条件
1: With ChirazymeTM L-2 in diethyl ether T=20°C; 30 h; 2: With sodium methylate in methanol T=20°C; 2 h;
参考文献
Izquierdo, Isidoro; Plaza, Maria T.; Rodriguez, Miguel; Tamayo, Juan A.; Martos, Alicia
Tetrahedron Asymmetry, 2001 , vol. 12, # 2 p. 293 - 300
反应条件
hydrogenchloride; (2,4-dinitro-phenyl)-hydrazine 12 h;
参考文献
MacNeil, Patricia A.; Roberts, Nicholas K.; Bosnich, B.
Journal of the American Chemical Society, 1981 , vol. 103, # 9 p. 2273 - 2280
反应条件
hydrogen; RuCl2[(R)-BINAP] in ethanol P=53200 Torr; 42 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 110, # 2 p. 629 - 631
反应条件
lithium aluminium tetrahydride in diethyl ether 5 h;
参考文献
Zarbin, Paulo H. G.; De Oliveira, Alfredo R. M.; Delay, Carlos E.
Tetrahedron Letters, 2003 , vol. 44, # 36 p. 6849 - 6851
反应条件
sodium tetrahydroborate in 1-methyl-pyrrolidin-2-one; methanol T=4°C; Inert atmosphere; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 10, # 24 p. 5581 - 5583
反应条件
RuH(η1-BH4)(dppp)((R,R)-dpen); hydrogen in tetrahydrofuran T=80°C; P=37503.8 Torr; 16 h; Autoclave;
参考文献
Advanced Synthesis and Catalysis, , vol. 352, # 1 p. 92 - 96
