(R)-(-)-1,3-丁二醇合成路线 (共 27 条)
反应条件
oxidoreductase CpSADH from Candida parapsilosis IFO 1396; β-NADP+ in aq. phosphate buffer Resolution of racemateEnzymatic reaction; stereoselective reaction;
参考文献
Organic Process Research and Development, , vol. 6, # 4 p. 558 - 561
参考文献
Tetrahedron Letters, , vol. 28, # 41 p. 4847 - 4848
参考文献
Chemistry Letters, , # 9 p. 1537 - 1540
反应条件
E. coli cells expressing CpSADH in phosphate buffer T=30°C; pH=6.8; 40 h; Enzymatic reaction; Product distribution; Further Variations:pH-valuesconcentrations;
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 66, # 4 p. 925 - 927
参考文献
Journal of Organic Chemistry, , vol. 47, # 20 p. 3850 - 3854
反应条件
triethylamine in dichloromethane T=20°C; 6 h;
参考文献
Izquierdo, Isidoro; Plaza, Maria T.; Rodriguez, Miguel; Tamayo, Juan A.; Martos, Alicia
Tetrahedron Asymmetry, 2001 , vol. 12, # 2 p. 293 - 300
反应条件
Candida antarctica lipase B T=40 - 45°C; P=8 - 10 Torr; 72 h; Microbiological reaction;
参考文献
Isis Innovation Limited; Government of the USA, as Represented by the Secretary , Department of Health And; Human Services
Patent: US2011/237666 A1, 2011 ;
Location in patent: Page/Page column 5 ;