in methanol; hexane; chloroform; ethyl acetate; acetonitrile

in methanol; hexane; chloroform; ethyl acetate; acetonitrile

ammonia Ambient temperature;

1: 98 percent / methanol; H2O; acetonitrile / Ambient temperature 2: 1.) aq. NaNO2, CuCl2 / 1.) RT, 2 h, 2.) H2O, 100 deg C, 1 h 3: acetonitrile / 0.33 h / 75 °C 4: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 16 h / Ambient temperature 5: 74 percent / methanolic ammonia / Ambient temperature View Scheme

1: 1.) aq. NaNO2, CuCl2 / 1.) RT, 2 h, 2.) H2O, 100 deg C, 1 h 2: acetonitrile / 0.33 h / 75 °C 3: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 16 h / Ambient temperature 4: 74 percent / methanolic ammonia / Ambient temperature View Scheme

1: acetonitrile / 0.33 h / 75 °C 2: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 16 h / Ambient temperature 3: 74 percent / methanolic ammonia / Ambient temperature View Scheme