1: pyridine / 3 h / 20 °C 2: 70 percent / NaI / acetone / 18 h / 20 °C 3: 1.) NaH / 1.) THF, DMF, 20 deg C, 10 min, 2.) reflux, 1 h View Scheme

1: BH3-Me2S complex / tetrahydrofuran / 1 h / 20 °C 2: pyridine / 3 h / 20 °C 3: 70 percent / NaI / acetone / 18 h / 20 °C 4: 1.) NaH / 1.) THF, DMF, 20 deg C, 10 min, 2.) reflux, 1 h View Scheme

1: 70 percent / NaI / acetone / 18 h / 20 °C 2: 1.) NaH / 1.) THF, DMF, 20 deg C, 10 min, 2.) reflux, 1 h View Scheme

sodium methylate

sodium hydride 1.) THF, DMF, 20 deg C, 10 min, 2.) reflux, 1 h; Yield given. Multistep reaction;