1: exo-N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)-2-methylpropanamide With phosphorus pentachloride in dichloromethane T=-5 - 20°C; 4 h; Inert atmosphere; 2: oxalic acid monohydrazide in 1,1-dimethylpropan-1-ol; acetonitrile T=10 - 20°C; 15.5 h; Inert atmosphere; 3: With oxalic acid monohydrazide in 1,1-dimethylpropan-1-ol; acetonitrile T=80°C; 2 h; Inert atmosphere;

hydrogenchloride Hydrolysis.das salzsaure Salz entsteht;

sulfuric acid in water T=80°C; reactions under var. conditions with HCl and HClO4; KineticsRate constant;

(i) KOH, aq. EtOH, (ii) aq. AcOH; Multistep reaction;

(i) aq. KOAc, (ii) N2H4*H2O, EtOH, (iii) aq. AcOH; Multistep reaction;