2-(3-吡啶基)-1-乙醇合成路线 (共 26 条)
反应条件
1: With methyl-diethoxy-silane; zinc diacetate in tetrahydrofuran T=65°C; 24 h; Inert atmosphere; 2: With methanol; potassium hydroxide chemoselective reaction;
参考文献
Das, Shoubhik; Moeller, Konstanze; Junge, Kathrin; Beller, Matthias
Chemistry - A European Journal, 2011 , vol. 17, # 27 p. 7414 - 7417
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether 2 h;
参考文献
Lowen, Gregory T.; Almond, Merrick R.; Rideout, Janet L.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 6 p. 1663 - 1665
参考文献
Eisai Co., Ltd.
Patent: US2002/19531 A1, 2002 ;
US 20020019531 A1
参考文献
The Upjohn Company
Patent: US4789745 A1, 1988 ;
反应条件
in tetrahydrofuran; diethyl ether; water
反应条件
ammonia; sodium in diethyl ether Birch reduction; 0.5 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 39, # 2 p. 335 - 339
反应条件
1: 80 percent / NaNH2 / diethyl ether / 0 - 20 °C 2: 1.) borane, 2.) NaOAc, H2O2 View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 51 p. 8329 - 8332
反应条件
sulfuric acid; sodium nitrite T=0°C; und anschliessenden Erwaermen;
参考文献
Chemische Berichte, , vol. 80, p. 505,507
反应条件
borane; dihydrogen peroxide; sodium acetate Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 34, # 51 p. 8329 - 8332