7-甲氧基-2-氧代-2H-1-苯并吡喃-4-乙酸合成路线 (共 17 条)
反应条件
sulfuric acid T=25°C; 48 h;
参考文献
Brubaker; DeRuiter; Whitmer
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1094 - 1099
反应条件
sodium hydroxide in ethanol 2 h; Heating;
参考文献
Ma, Yongmin; Luo, Wei; Quinn, Peter J.; Liu, Zudong; Hider, Robert C.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6349 - 6362
反应条件
potassium hydroxide T=20°C; 1 h;
参考文献
Dubovik; Garazd; Khilya
Chemistry of Natural Compounds, 2004 , vol. 40, # 5 p. 434 - 443
反应条件
1: 62 percent / Amberlyst-15 cation-exchange resin / toluene / 10 h / Heating 2: 80 percent / aq. NaOH / ethanol / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6349 - 6362
反应条件
1: 62 percent / Amberlyst-15 cation-exchange resin / toluene / 10 h / Heating 2: 80 percent / aq. NaOH / ethanol / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6349 - 6362
参考文献
Journal of the American Chemical Society, , vol. 72, p. 3987,3989
参考文献
Journal of the Chemical Society, , vol. 107, p. 1637
反应条件
1: 60 percent / HCl / methanol / 3 h 2: 88 percent / K2CO3 / acetone / 1 h / 50 - 56 °C 3: 74 percent / aq. KOH / 1 h / 20 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 40, # 5 p. 434 - 443
反应条件
1: 88 percent / K2CO3 / acetone / 1 h / 50 - 56 °C 2: 74 percent / aq. KOH / 1 h / 20 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 40, # 5 p. 434 - 443
反应条件
1: 60 percent / HCl / methanol / 3 h 2: 88 percent / K2CO3 / acetone / 1 h / 50 - 56 °C 3: 74 percent / aq. KOH / 1 h / 20 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 40, # 5 p. 434 - 443