1-(3,6-二氢-2H-吡喃-4-基)吡咯烷合成路线 （共 3 条）
反应条件
Carbamonitrile; sulfur in methanol 72 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1405852 A1, 2004 ;
Location in patent: Page 74 ;
EP 1405852 A1
反应条件
in benzene
4 h; Heating;
参考文献
Friary; Seidl; Schwerdt; Cohen; Hou; Nafissi
Tetrahedron, 1993 , vol. 49, # 33 p. 7169 - 7178
反应条件
1: With 4-(N,N-dimethlyamino)pyridine in N,N-dimethyl-formamide
T=0°C; 1 h;
2: With hydrogenchloride; water
2 h;
参考文献
MERCK and CO., INC.; MERCK SHARP and DOHME LIMITED
Patent: WO2003/93266 A1, 2003 ;
Location in patent: Page/Page column 21-22 ;
WO 03/093266 A1
