((3aR,4S,6aS)-5-乙酰氧基-2-氧代六氢-2H-环戊并[b]呋喃-4-基)甲基 乙酸酯合成路线 （共 4 条）
反应条件
Amberlite IR 120 resin in methanol T=70°C; 8 h;
参考文献
Toemoeskoezi, Istvan; Gruber, Lajos; Baitz-Gacs, Eszter
Tetrahedron, 1992 , vol. 48, # 47 p. 10345 - 10352
反应条件
1.1: DBN / methanol / 12 h / 20 °C 2.1: 1H-imidazole / N,N-dimethyl-formamide / 0.33 h / 20 °C / |Inert atmosphere 2.2: 8 h / |Inert atmosphere 3.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Gonzalez-Gonzalez, Carlos A.; Fuentes-Benitez, Aydee; Cuevas-Yanez, Erick; Corona-Becerril, David; Gonzalez-Romero, Carlos; Gonzalez-Calderon, Davir
Tetrahedron Letters, 2013 , vol. 54, # 21 p. 2726 - 2728
反应条件
1.1: methanol / 25 - 65 °C 2.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / tetrahydrofuran / 35 - 65 °C / |Inert atmosphere; |Molecular sieve 3.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 0.17 h / 27 °C / |Inert atmosphere 3.2: 35 - 40 °C / |Inert atmosphere View Scheme
参考文献
Jackson, Mark; Dahanukar, Vilas Hareshwar; Joseph, Suju Chuttippari; Eda, Vishnu Vardhana Verma Reddy; Ramdas, Sandip Khobare
Patent: US2013/184476 A1, 2013 ;
反应条件
1.1: DBN / methanol / 12 h / 20 °C
2.1: 1H-imidazole / N,N-dimethyl-formamide / 0.33 h / 20 °C / |Inert atmosphere
2.2: 8 h / |Inert atmosphere
View Scheme
参考文献
Gonzalez-Gonzalez, Carlos A.; Fuentes-Benitez, Aydee; Cuevas-Yanez, Erick; Corona-Becerril, David; Gonzalez-Romero, Carlos; Gonzalez-Calderon, Davir
Tetrahedron Letters, 2013 , vol. 54, # 21 p. 2726 - 2728
