5,6-二甲氧基-1,3-苯并噻唑-2-胺合成路线 (共 5 条)
参考文献
Metten, Bert; Smet, Mario; Boens, Noel; Dehaen, Wim
Synthesis, 2005 , # 11 art. no. T13704SS, p. 1838 - 1844
反应条件
1: ammonium thiocyanate With bromine in acetic acid
T=10°C;
2: 4-amino-1,2-dimethoxybenzene in acetic acid
T=10°C; 19 h;
参考文献
Hirose, Wataru; Sato, Kousuke; Matsuda, Akira
European Journal of Organic Chemistry, 2011 , # 31 p. 6206 - 6217
反应条件
bromine; acetic acid
T=0°C; 2 h; Cooling with ice;
参考文献
Ismail, Mohamed A. H.; Tratrat, Christophe; Haroun, Michelyne G.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2013 , vol. 28, # 6 p. 1331 - 1345
反应条件
in methanol; diethyl ether
Ambient temperature;
参考文献
Teitei, Tsutomu
Australian Journal of Chemistry, 1983 , vol. 36, # 11 p. 2307 - 2316
反应条件
tert.-butylnitrite; copper dichloride in acetonitrile
Sandmeyer reaction;
参考文献
Metten, Bert; Smet, Mario; Boens, Noel; Dehaen, Wim
Synthesis, 2005 , # 11 art. no. T13704SS, p. 1838 - 1844